Histology Technician/ Histotechnologist

Cleveland Clinic · Cleveland Clinic Main Campus

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At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day.

We all have the power to help, heal and change lives — beginning with our own. That’s the power of the Cleveland Clinic Health System team, and The Power of Every One.

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*This position is eligible for a sign-on bonus of 5,000* 

Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world. 

At Cleveland Clinic, every detail matters when it comes to delivering exceptional patient care—and that starts in the lab. As a Histotechnologist or Histology Technician, you’ll play a vital role behind the scenes, preparing high-quality tissue samples that support accurate diagnoses and life-changing treatment decisions. 

In this role, you’ll bring precision, technical expertise and attention to detail to every specimen, working as part of a collaborative team dedicated to excellence. Your contributions will directly impact patient outcomes, ensuring physicians have the information they need to provide the best possible care. 

Join a team that values your skills, supports your growth and empowers you to make a meaningful difference every day. 

We will hire our histology laboratory personnel into one of two job titles based on educational background, certification, and experience: 

• Histology Technician 

• Histotechnologist 

The caregiver in this role works full-time, evenings, 4:00pm—12:30am. 

Histology Technician Role: 

A caregiver who excels in this role will:  

• Prepare, process, embed and section tissue specimens using standard histology equipment, including microtomes and cryostats  

• Perform routine and specialized staining procedures, including histochemical and enzyme stains  

• Mount, label, and distribute slides for pathologist review  

• Maintain laboratory equipment, perform daily maintenance and coordinate repairs as needed  

• Prepare reagents, buffers and solutions to support testing procedures  

• Accurately document patient and specimen data, maintain records and track lab statistics  

• Ensure cleanliness, organization and quality control of lab instruments and workspaces  

• Support training and serve as a resource for students, trainees and residents 

Minimum qualifications for the ideal future caregiver include:  

• American Society for Clinical Pathology (ASCP) Certification eligible in the field of Histology 

Preferred qualifications for the ideal future caregiver include: 

• One year of experience 

Histotechnologist Role: 

A caregiver who excels in this role will: 

• Perform routine and developmental immunochemistry and molecular laboratory techniques.  

• Analyze and evaluate assays for sensitivity and specificity.  

• Embed and prepare sections for various procedures by cutting off frozen or paraffin embedded tissue. 

• Transport tissue specimens to the laboratory.  

• Perform immunohistochemical and in-situ hybridization procedures, including handling and storing probes and antibodies.  

• Mount, label and distribute prepared microscope slides.  

• Prepare reagent buffers, solutions and stains.  

• Replace reagents and perform daily maintenance on automated instrumentation.  

• File surgical and autopsy blocks used for immunohistochemical techniques.  

Minimum qualifications for the ideal future caregiver include:  

• Bachelor’s Degree in Biology, Microbiology, Chemistry or a related field or meet the CLIA qualifications for Histotechnologist (HTL)  

• Histotechnician (HT) or Histotechnologist (HTL) certification or certification eligible by the American Society for Clinical Pathology (ASCP)  

• Working knowledge of OSHA requirements concerning chemical hygiene and bloodborne pathogens  

Preferred qualifications for the ideal future caregiver include: 

• Hands-on laboratory experience from an accredited Histotechnology school or one year of prior histology laboratory experience   

*The compensation range provided corresponds to the Histotechnologist/Histology Technician position. Individual pay rates may vary based on licensure level, certification, and relevant experience.*

Physical Requirements:

• Requires manual dexterity and visual acuity when handling specimens, slides and utilizing instrumentation.
• Ability to safely handle potentially infectious patient specimens, carcinogenic substances, odorous and other hazardous materials to which they may be exposed.
• Typical physical demands include ability to sit, stand or walk extensively.

Personal Protective Equipment:

• Follows standard precautions using personal protective equipment as required.

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility. 

If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/

Please review the Equal Employment Opportunity poster. 

Cleveland Clinic is pleased to be an equal employment opportunity employer.

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