Cloud Solution Engineer (Genomics & AI)

Oracle · United States

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• Design and demonstrate genomic analysis workflows, including WGS/WES germline and somatic variant calling, bulk RNA-seq, and single-cell analysis. Apply appropriate quality control, processing, and interpretation methods for each data type.

• Design computational solutions for functional genomics and genome engineering research, including CRISPR screen analysis, gene regulation, perturbation response, and therapeutic target identification and prioritization. Partner with experimental scientists to connect model predictions with biological validation.

• Develop and evaluate AI/ML approaches for variant prioritization, multi-omics integration, biomarker discovery, and genotype–phenotype modeling. Assess genomic foundation models and sequence-based deep learning where they address a defined scientific question.

• Build reproducible pipelines using Python or R, workflow orchestration, containers, version control, and automated testing. Integrate sequencing platforms, laboratory information management systems, sample metadata, and downstream analytical applications.

• Architect CPU and GPU computing, storage, networking, and data platforms on OCI. Benchmark accelerated genomics and model training or inference against customer baselines for accuracy, throughput, turnaround time, and cost per sample.

• Establish sound model evaluation with appropriate cohort separation, controls for data leakage and batch effects, subgroup analysis, and uncertainty assessment. Maintain data provenance, pipeline and model versioning, and reproducibility.

• Lead customer workshops, demonstrations, and proofs of concept with agreed success criteria. Communicate findings, architecture tradeoffs, costs, and recommendations through presentations and written proposals that support customer decisions and production planning.

• Partner with sales, product, and engineering teams; advise scientific and executive stakeholders; mentor colleagues; and publish reusable architectures, solution code, and technical content. Bring customer requirements into product roadmap discussions.
   

• Eight or more years of relevant technical experience, including hands-on work, in bioinformatics, computational genomics, scientific computing, cloud engineering, or closely related areas.

• Demonstrated ability to build and troubleshoot genomic analysis workflows, with a strong understanding of sequencing data, genomic variation, statistical analysis, and the biological interpretation of results.

• Strong programming skills in Python and working proficiency in R or an equivalent scientific computing language. Experience with Linux, Git, containers, and workflow tools such as Nextflow, WDL/Cromwell, or Snakemake.

• Practical experience developing, evaluating, or deploying machine learning models for biological or other complex scientific datasets, using frameworks such as PyTorch, TensorFlow, or scikit-learn.

• Experience designing cloud or high-performance computing solutions, including compute and storage sizing, workflow scheduling, security, performance optimization, and cost management.

• Demonstrated executive presence, strong interpersonal skills, and clear verbal and written communication. Able to translate complex scientific and technical requirements into actionable recommendations, build trusted relationships with researchers and senior decision-makers, and connect technical tradeoffs to business priorities, costs, and measurable outcomes.

• Ability to travel up to 50 percent domestically and internationally.

• Bachelor’s degree in bioinformatics, computational biology, computer science, genetics, engineering, mathematics, or a related field, or equivalent relevant experience. An advanced degree in a relevant field is highly desirable.

• Depth in one or more areas: population or translational genomics; oncology and liquid biopsy; rare disease analysis; single-cell or spatial omics; epigenomics and 3D genome biology; or CRISPR and perturbation-based functional genomics.

• Experience with tools such as GATK, DeepVariant, NVIDIA Parabricks, or comparable genomics software; GPU acceleration; distributed computing; and large-scale genomic datasets.

• Experience adapting genomic or biological foundation models, integrating multimodal biological data, or building evidence-grounded AI assistants for scientific workflows.

• Familiarity with OCI or another major cloud platform, Kubernetes, infrastructure as code, experiment tracking, and model deployment and monitoring.

• Experience supporting sensitive genomic data with access controls, encryption, audit trails, consent-aware data use, and customer validation requirements.

• Customer-facing solution architecture, technical consulting, or presales experience, including proofs of concept and successful transitions to production.

Customers select and adopt OCI based on demonstrated scientific value and a compelling business case. Proofs of concept meet agreed success criteria, demonstrate measurable improvements against customer baselines, and establish a credible path to production. Reusable solutions accelerate subsequent customer evaluations and adoption.

Only Oracle brings together the data, infrastructure, applications, and expertise to power everything from industry innovations to life-saving care. And with AI embedded across our products and services, we help customers turn that promise into a better future for all. Discover your potential at a company leading the way in AI and cloud solutions that impact billions of lives.

True innovation starts when everyone is empowered to contribute. That’s why we’re committed to growing a workforce that promotes opportunities for all with competitive benefits that support our people with flexible medical, life insurance, and retirement options. We also encourage employees to give back to their communities through our volunteer programs.

We’re committed to including people with disabilities at all stages of the employment process. If you require accessibility assistance or accommodation for a disability at any point, let us know by emailing accommodation-request_mb@oracle.com or by calling 1-888-404-2494 in the United States.

Oracle is an Equal Employment Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability and protected veterans’ status, or any other characteristic protected by law. Oracle will consider for employment qualified applicants with arrest and conviction records pursuant to applicable law.

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