[MA] Senior Medical Affairs Scientist Manager - Amyloidosis (Cardiology)
Pfizer · Tokyo
MAIN RESPONSIBILITIES / DUTIES
JOB POSITION PURPOSE
• Act as the Amyloidosis team lead and line manager, leading a team of MAS. Shape the local strategy and ensure the delivery of scientific‑medical expertise and exchange with leading cardiologists, heart failure specialists, and multidisciplinary amyloidosis centers across Japan. Leverage deep cardiology expertise (particularly in heart failure, cardiomyopathy, and infiltrative cardiac disease) to establish Pfizer as a trusted scientific partner in the evolving amyloidosis treatment landscape, bridging clinical insights with Medical Affairs excellence.
- Focus on designated products through a team of MAS.
- Lead Pfizer Japan as the medical and scientific point of contact for HCPs, medical societies, regulators, academia, and other external stakeholders.
- Play a central role as a scientific and medical leader, identifying unmet medical needs (UMRs), driving the development and execution of medical plans, and overseeing the establishment of clinical evidence.
- Ensure and oversee the highest scientific standards during internal and external activities, providing deep medical and scientific expertise.
- Direct and supervise the provision and exchange of medical/scientific information to and from medical facilities in the assigned area and external stakeholders and make strategic decisions on medical strategies for assigned products to ensure safe, proper, and effective use. These activities contribute to patients and healthcare professionals from medical, pharmaceutical, and clinical study perspectives.
- Drive and monitor a heightened understanding of disease burden in the assigned therapeutic area and the medical attributes of products to enhance safe and effective use.
- Lead the achievement of department and team goals, and/or manage cross‑organizational projects, providing guidance and accountability for results.
Develop and Execute the Medical Plan
- Develop and execute the Medical Plan aligned with medical strategy to address UMRs in assigned product(s) and therapeutic area(s).
- Oversee identification of UMRs and healthcare disparities, and manage execution of customer‑facing medical activities, including unbiased medical and scientific communication with HCPs and relevant organizations, advisory boards, educational seminars, data‑generation initiatives, medical material development, and scientific input.
- Approve and guide medical activity plans to address unmet needs and data gaps in accordance with therapeutic area strategy.
- Lead creation of the Customer‑Facing component of the Medical Plan and ensure strategic alignment with stakeholders.
- Provide subject‑matter expertise and high‑quality scientific exchange, bringing insights into the organization to shape strategy.
Collaborate with Medical Stakeholders
- Lead establishment of strong, collaborative scientific relationships with Japan’s leading cardiologists, amyloidosis specialists, and multidisciplinary centers through non‑promotional, peer‑to‑peer scientific exchange.
- Direct maintenance of a comprehensive stakeholder map and ensure effective communication strategies.
Demonstrate Medical and Scientific Leadership
- Oversee compliance in investigator‑sponsored research and medical grants in accordance with Pfizer policies.
- Acquire and maintain up‑to‑date medical and pharmaceutical knowledge to support medical strategy.
- Deliver key medical activities, including generation of real‑world evidence, educational materials, non‑interventional studies, database studies, and registries, ensuring timely publication.
Establish Long‑Term Stakeholder Relationships
- Drive evidence‑generation opportunities through internal and external collaboration.
- Ensure patient‑centricity of medical communications, incorporating health literacy and cultural awareness.
- Build and maintain peer‑to‑peer scientific relationships with HCPs and decision‑makers.
- Ensure collection and analysis of insights prior to meetings to provide deep scientific expertise.
Internal Collaboration
- Lead provision of expert feedback on product life‑cycle strategies.
- Ensure appropriate sharing of medical insights with Marketing colleagues within compliance boundaries.
- Provide scientific support and approval of promotional materials.
- Contribute scientifically to early benefit assessments, pricing, reimbursement strategies, and dossiers.
- Serve as the point of contact for medical and product‑related inquiries.
- Actively participate in regional and global disease‑area strategy teams.
Clinical Development Collaboration
- Provide medical input into protocol feasibility assessments.
- Collaborate with Development Japan (DJ) and global development on investigator and site selection.
- Support timely completion of Pfizer‑sponsored clinical trials.
- Provide strategic medical input into global clinical programs, ensuring relevance to Japan.
- Support DJ in regulatory interactions from early development phases.
Data Communication and Insights
- Oversee provision of accurate, unbiased medical information, including unsolicited requests.
- Lead collection and strategic use of insights to inform medical strategy.
- Oversee local advisory boards to gather customer insights.
- If media‑trained, represent scientific perspectives during media briefings.
Compliance and Safety
- Ensure compliance with Medical Affairs codes of conduct.
- Conduct activities in compliance with MHLW guidelines.
- Ensure adherence to safety reporting obligations and required training.
Financial Accountability
- Support preparation and management of the medical budget, coordinating with CMD and internal departments.
- Train MAS teams on budget accountability.
People Management Accountability
- Demonstrate strong leadership, fostering an inclusive and collaborative environment.
- Support career development through coaching and feedback.
- Lead a team of MAS as a direct supervisor, with matrix responsibility across functions.
- Confidently engage in both small and large settings, navigating complex discussions effectively.
AS NEEDED
- Contribute to Business Development activities, identifying UMRs and candidate therapies while maintaining confidentiality.
- Lead rapid medical response to critical supply issues.
REQUIRED SKILL SET
Education- MD with cardiology background preferred.
- Clinical experience in heart failure, cardiomyopathy, or amyloidosis highly valued.
- PhD or clinical research experience a plus.
• Strategic thinking, communication, decision‑making, leadership, financial acumen, and compliance.
People Management Skills• Coaching, teamwork, problem‑solving, and resource management.
Advanced Scientific/Medical Expertise and Industry Knowledge- Practical expertise in the relevant field and KOL management.
- Medical strategy development across pipeline, pre‑launch, and LOE phases.
- Scientific publication experience as first author.
- Broad drug development and post‑marketing experience.
- Strong understanding of compliance and SOPs.
Experience
- Clinical cardiology or amyloidosis research background strongly preferred.
- Experience in Medical Affairs, Clinical Development, or MSL roles advantageous.
- Scientific publication and congress presentation experience preferred.
- People management or team leadership experience preferred.
Language
- Proficiency in English and Japanese required.
- Minimum TOEIC score of 730
Work Location Assignment: Hybrid
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

Medical